VIDEO TESTATA 1

NATURAL HELP TO IMPROVE AND PROTECT COGNITIVE BRAIN FUNCTIONS

PRODOTTO 2

COGNIGRAPE™ is a standardized powder extract from red grape juice containing high concentrations of active grape substances such as anthocyanins and proantocyanidins.

COGNIGRAPE™ is an ingredient developed by BIONAP to improve cognitive performance and prevent brain aging.

The increase in life expectancy is associated with gradual aging of the population. This epochal change creates new needs. It has been observed that memory ability decreases with age.

Ageing is not a burden, and every person should have the opportunity to live a long and healthy life, making valuable and important contributions to society. Moreover, nowadays, information are going faster than ever.

We are constantly solicited by an uninterrupted flow of data. In this context, improving attention, language and memory performance, has become a need in order to adapt and perform in modern life.

Grapes are a type of fruit that grow in clusters of 15 to 300.
Anthocyanins and other pigment chemicals of the larger family of polyphenols in purple grapes are responsible for the varying shades of purple in red wines. Grapes are typically an ellipsoid shape resembling a prolate spheroid.

APPLICAZIONI 3

WHAT IT DOES

The grape polyphenolic compounds contained in COGNIGRAPE™ can be considered as a natural aid in preventing cognitive deterioration, mainly thanks to their antioxidant effect.
COGNIGRAPE™ supplementation hasbeen clinically proven to improve cognitive function such as attention, language, immediate and delayed memory and, at the same time, it is able to ameliorate the mood status in healthy older subjects.
STUDI SCIENTIFICI 4

CLINICAL EVALUATION
OF COGNIGRAPE™ EFFECT

COGNIGRAPE™ effect in brain function has been recently evaluated in randomized, double-blind, placebo control clinical trial carried out
- on 111 subjects of healthy older adults (mean age 66.9±5.2 years);
- treated with 250 mg of COGNIGRAPE™;
- once a day for 12 weeks by using Mini-Mental State Examination (MMSE) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).
COGNIGRAPE™ supplementation was able to increase MMSE and RBANS score and improve the mood status thanks to to the better cognitive performance and general neuropsychological subject condition.

MMSE
Mini-Mental
State
Examination

MMSE score before and after supplementation with COGNIGRAPE™ (250 mg/die for 12 weeks) and placebo (*p0.0001 vs placebo).

RBANS
Assessment of
Neuropsychological
Status

RBANS score before and after supplementation with COGNIGRAPE™ (250 mg/die for 12 weeks) and placebo (*p0.0001 vs placebo).

+6.2% OF ATTENTION, LANGUAGE, IMMEDIATE AND DELAYED MEMORY